In Dragon Ball, Goku first uses the Bending Kamehameha to cause an avalanche to fall on Ninja Murasaki during the Red Ribbon Army Saga, and later uses the Bending Kamehameha to directly hit King Piccolo in the head during the King Piccolo Saga. In Dragon Ball Z, Goku uses the Bending Kamehameha against Raditz during the Saiyan Saga, but Raditz easily blocks it. While traveling to Namek during the Namek Saga, Goku fires Bending Kamehameha waves around the Capsule Corporation spaceship he is using in order to get Zenkai and increase his power. When fighting Captain Ginyu during the Ginyu Saga, Goku uses a Kamehameha, but he has lost so much power that it bends away from Ginyu.

Krillin uses it against Garlic Jr. during the Garlic Jr. Saga, performing it like his Scattering Bullet technique.

During the Cell Games Saga, Cell uses a similar technique during his fight with Goku, when Goku attempts to get Cell to divert the Kamehameha upwards in order to keep it from destroying Earth (Cell charges it with enough power to destroy the planet).

During the Fusion Saga, the Ghost Buus use a homing Multiple Kamehameha attack against Super Vegito, chasing him quickly across the sky until trapped in a valley.

During the Shadow Dragon Saga, Omega Shenron is seen doing the stance of the kamehameha wave and performs it nearly identical to Goku's previous kamehameha wave against him and used it to attack Super Saiyan 4 Goku,

In the movie Dragon Ball Z: Battle of Gods, Goku fires a Kamehameha which he redirects at himself and blocks while preparing on King Kai's planet for the second fight with Beerus.

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