Elizabeth "Betty" Jean Rubble is a cartoon character in the television animated series The Flintstones and its spin-offs and live-action motion pictures. She is the black-haired wife of caveman Barney Rubble and the adoptive mother of Bamm-Bamm Rubble. Her best friends are her next-door neighbors, Fred and Wilma Flintstone.
Betty lives in the fictional prehistoric town of Bedrock, a world where dinosaurs coexist with cavepeople and the cavepeople enjoy primitive versions of modern conveniences such as telephones, automobiles and washing machines.
Betty's personality was based on that of Trixie Norton, wife of Ed Norton on the 1950s television series The Honeymooners; each of the four of the series' principal adult characters is an analogue of a Honeymooners character. Much as Trixie spent a lot of her time socializing with Alice Kramden, Betty spent a lot of her time socializing with Wilma, and the two would often end up working together to bail their husbands out of whatever scheme of Fred's had landed them in trouble.
Betty is rarely seen failing to follow the lead of Barney or Wilma, so may appear to be the least developed character in the show. In spite of this, Betty is portrayed as having a distinctly emotional marriage with Barney, which often includes pet names and more obvious affection than the dynamic and energetic interaction between Fred and Wilma. Occasions when Betty leads the action are extremely scarce: one episode centers around her working undercover as a gentle old lady to earn money for a present for Barney; in another the plot focuses on her and Wilma's suspicions of Barney being involved with another woman (who turns out to be Fred in a disguise in order to attend a ball game free of charge). This lack of protagonism (her continuous presence almost becoming a backdrop for supporting characters Pebbles, Bamm-Bamm and Dino) makes Betty less of the lead that the show's general concept might imply.
While the mid-1980s spin-off series The Flintstone Kids depicts Betty as a child, the series seems to be mostly apocryphal, owing to its presenting Betty as a childhood friend of Fred and Barney (the original series asserts that they first met as young adults) and that they enjoy watching a TV show starring Captain Caveman (The Flintstone Comedy Show asserts that the adult Betty is ignorant of Captain Caveman's superhero identity when working with him at the Daily Granite newspaper). The series also erroneously refers to Betty's last name as "Bricker," not "McBricker." Still, the series' assertions that Betty was a childhood friend of Wilma, that she has an older brother named Brad, and that her parents ran a convenience store may be considered canon.
As young adults, Betty and Wilma were employed as cigarette girls/waitresses at a resort. There, they first met, and fell in love with their future husbands, Fred and Barney. Eventually, Betty and Barney were married, presumably not long after Fred and Wilma.
Betty became a homemaker, keeping house with such prehistoric aids as a baby mammoth vacuum cleaner, pelican washing machine, and so forth. Betty, much like Wilma, also enjoyed volunteering for various charitable/women's organizations in Bedrock, shopping, and (occasionally) meeting the celebrities of their world, including "Stony Curtis", "Cary Granite", and "Ann-Margrock". Betty at one time also had a job working for an 'old lady' who turned out to be a young lady in disguise and who was using Betty to pass counterfeit money; this was the only episode centered principally around Betty. 
In the fourth season of the original series, Betty and Barney found an abandoned infant on their doorstep, by the name of "Bamm-Bamm." After a court battle for possession of Bamm-Bamm (in which the Rubbles faced the opposition's noted prehistoric lawyer "Perry Masonry"), the couple were allowed to adopt Bamm-Bamm. The Rubbles never had children of their own.
When Bamm-Bamm was a teenager, Betty gained employment as a reporter for one of Bedrock's newspapers, the Daily Granite(presumably a parody of the Daily Planet of Superman fame), under the editorial guidance of Lou Granite (presumably a parody ofLou Grant of the contemporaneous eponymous series, and formerly of The Mary Tyler Moore Show). While employed there, she shared various adventures with prehistoric superhero Captain Caveman, who (in a secret identity) also works for the newspaper.
Later still, after Bamm-Bamm grew up and left home, Betty started a successful catering business with her neighbor and friend Wilma, before becoming a grandmother to Bamm-Bamm's twin children, Chip and Roxy.
June Foray voiced Betty in the original pilot titled The Flagstones, although she was busy with other projects at the time- (such as The Rocky and Bullwinkle Show) and was unable to sign on as a regular voice for the series. Bea Benaderet voiced Betty from seasons one to four before resigning in 1964 due to the workload on Petticoat Junction.Gerry Johnson took over the role for the fifth and sixth seasons, as well as The Man Called Flintstone film before taking leave shortly afterward. Gay Autterson Hartwig voiced her throughout the 1970s through the early 1980s. Julie McWhirter Dees voiced her in mid to late 1980s. Betty Jean Ward voiced her throughout the 1990s. Grey DeLisle has since performed the role in later Flintstones media since 2000.
In the 1994 film, Betty was portrayed by Rosie O'Donnell, a casting decision somewhat controversial with fans as the plus-sized O'Donnell did not match Betty's slender figure from the animated series; O'Donnell reportedly won the role because she captured the high pitch laugh at her audition. Jane Krakowski's version of the character in the second movie was generally received better, though was largely overlooked owing to the film's poor overall reception. Her last name in the film is O'Shale in this version.
- Betty has been seen in the Dexter's Laboratory episode Dad is Disturbed talking to Dexter's Mom, but was tied up by Dexter's Dad.
- Betty has been seen in the I Am Weasel episode I Am My Lifetime, where she is placed in the Retirement Home for Sidekicks (which is actually Baboon's trailer).
- In the Comedy Central animated film The Drawn Together Movie: The Movie!, she can be seen trying to kill Toot Braunstein (she misses and shoots a dinosaur instead), for finding out that her husband Barney Rubble cheated on her and impregnated Toot (Toot's baby is revealed to be Bamm-Bamm Rubble).
- In The Grim Adventures of Billy and Mandy episode "A Grim Prophecy," Grim is shown as a child in the Stone Age, just starting his job as the Grim Reaper. He has a list of living things to reap, and visible on the list is "B. Rubble," which could be either Barney or Betty. During the credits sequence of the episode "Modern Primitives," Betty is seen in the kitchen as Barney answers the doorbell. The visitor is Billy, who makes unintelligible noises before Barney clubs him on the head. Betty asked who was at the door, to which Barney replies "Proof against evolution," laughing.