Bill Clinton was the 42nd President of the United States, and the incumbent President during the run of Animaniacs, Pinky And The Brain, and other Warner Bros. shows, so he was often featured in them. During his appearances on the show he was voiced by Frank Welker. He really does play the saxophone (as one of the Animaniacs theme song references) and made a famous appearance on the Arsenio Hall Show during his first presidential campaign.
- Bill Clinton is seen as a kid in Puppet Rulers.
- Bill Clinton is the last president in The Presidents, along with his wife, Hillary Clinton.
- Bill Clinton often appeared in the Pinky And The Brain spin-off, mainly because many episodes involved world leaders.
- Bill Clinton was referenced in Theme song in the lyrics "while Bill Clinton plays the sax" wherein Bill Clinton Himself is playing the saxophone. Yakko and Wakko pops out from the saxophone while Dot is hanging on to Bill Clinton's shoulders.