The chakra scalpel can also be used offensively, although it requires great precision to be effective. Because of this requirement, using the chakra scalpel offensively is highly unusual. In heated combat, even the greatest medical-nin won't be able to exert the precision needed to make fatal cuts, but it can still effectively cut muscle tissues and tendons, rendering the target immobile.
In Part II though, Kabuto's skill with this technique was enough to cut through wood and flesh with ease.
- Although it is usually written in katakana, the "mesu" (メス, scalpel) part of the name was given kanji when it was first introduced. It was written as チャクラ解剖刀 (Literally meaning: Chakra Dissection Blade), which would usually be pronounced as "Chakura Kaibōtō". "Mesu" is derived from the word "Mes", which is scalpel in Dutch.
- Shizune uses this technique as a major portion of her fighting style in the Ultimate Ninja game series.