Michelle LaVaughn Robinson Obama is the wife of the forty-fourth President of the United States, Barack Obama, and is the first First Lady of the United States of African-American heritage.

In an extended scene in "Stewie Is Enceinte", Stewie asks Dr. Hartman if they should send the bill to President Obama following his prenatal care examination. A cutaway to Obama shows him making one of his speeches about the benefit of the Affordable Care Act, commonly known as "Obamacare." He uses Stewie's persona of "Rayleen Griffin" as one of his examples of people who would benefit. In the audience, Stewie sits with Michelle and asks to talk with her about the place where they have been given a room while in town.

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